Your nervous system — made up of the brain, spinal cord, and peripheral nerves — is the body’s command centre. It:

• Controls movement, sensation, and reflexes.
• Regulates mood, sleep, stress responses, and memory.
• Coordinates hormonal and immune responses through nerve signalling.
• Supports cognitive performance and emotional balance.

A healthy nervous system allows you to think clearly, react appropriately, manage stress, and recover from daily challenges. Signs of Nervous System Imbalance include:

• Chronic stress or anxiety
• Sleep disturbances or insomnia
• Brain fog, poor memory or focus
• Irritability or mood swings
• Tension, muscle tightness, or fatigue
• Poor balance, tripping 
• Exercise intolerance especially for anything involving jumping or balancing (which tax the nervous system versus musculature)

These symptoms often reflect dysregulation in neurotransmitters (chemical messengers like GABA, dopamine, serotonin, and glutamate), inflammation, or impaired nerve signalling.

Nutraceutical Support: What the Evidence Says

Below are key nutrients and botanicals that research suggests may support nervous system health — including brain function, stress response, and relaxation.

1. Clear Mind and Sleep 

Glycine: Glycine is a simple amino acid that also functions as an inhibitory neurotransmitter in the central nervous system, helping balance neural excitation.

Evidence highlights: Clinical studies in psychiatric populations showed improved symptoms and potential nervous system benefits with longer-term glycine administration, though evidence in healthy individuals remains limited. Glycine is also involved in synthesizing glutathione, a key antioxidant protecting neurons.

Benefits: May support calming neurotransmission, sleep quality, and emotional balance.

Magnesium Threonate (Magnesium L-Threonate):  Magnesium plays a central role in nerve transmission, muscle relaxation, and regulating neurotransmitters like GABA and glutamate. Magnesium L-threonate is a form shown to cross the blood–brain barrier more effectively than some other magnesium forms.

 Evidence highlights:A randomized, placebo-controlled trial in older adults reported significant improvements in cognitive performance, anxiety, and sleep after taking magnesium threonate for 12 weeks.

 Observational research links higher magnesium intake with better cognitive function and lower risk of mild cognitive impairment.

 Benefits: Cognitive support, mood regulation, stress resilience.

 L-Theanine: L-theanine, an amino acid found in tea leaves, promotes alpha brain wave activity, associated with relaxed alertness, and influences GABA, serotonin, and dopamine pathways.

 Evidence highlights: Randomized controlled trials show L-theanine may reduce subjective stress/anxiety and improve sleep quality and attention.

Benefits: Calm focus, reduced stress, sleep support.

Passionflower (Passiflora incarnata):

Traditionally used as a nervine herb to support relaxation and sleep.

Evidence highlights: Some double-blind, placebo-controlled studies found passionflower performed similarly to mild anxiolytic medications for anxiety symptoms.

Benefits: Stress relief, support for mild nervous tension and relaxation, assistance with healthy sleep patterns.

Lion’s Mane (Hericium erinaceus): A medicinal mushroom thought to stimulate nerve growth factor (NGF) production, potentially supporting neuron maintenance and regeneration.

Evidence highlights: Clinical trials in older adults with mild cognitive impairment found improvements in cognitive scores compared to placebo after 8–16 weeks of supplementation.

Benefits: Cognitive health, neurotrophic support.

Skullcap (Scutellaria spp.): Herbal nervine with traditional calming use.

Evidence highlights: Preliminary evidence suggests skullcap may promote relaxation and improve sleep.

Benefits: Calming support, stress reduction.

Tryptophan: An essential amino acid and precursor to serotonin and melatonin, both important for mood and sleep regulation.

Evidence highlights: Research suggests tryptophan can influence sleep and mood via serotonin and melatonin pathways, though clinical trials vary in outcomes.

Benefits: Sleep quality, balanced mood.

 

2. Clear Omega 

Omega-3 Marine-Based Oils (EPA & DHA): Long-chain omega-3s from fish (like EPA and DHA) are critical structural components of neuron membranes and influence membrane fluidity and signalling.

Evidence highlights: Systematic reviews and meta-analyses suggest modest improvements in certain aspects of cognitive function with omega-3 supplementation in adults.

Omega-3 intake is linked to better brain development, neurotransmission, and mental health outcomes in various populations.

Benefits: Neuroprotection, cell signalling support, cognitive maintenance.

 

3. Clear Recovery (Key Nutrients Taurine and Creatine plus Antioxidants Including Resveratrol)

Taurine: A sulfur-containing amino acid highly concentrated in the brain, retina, and nervous tissue. It plays a critical role in neuronal excitability, neurotransmitter modulation, calcium balance, and neuroprotection. Taurine interacts with GABA and glycine receptors, contributing to inhibitory (calming) neurotransmission and helping prevent overstimulation of neurons.

Evidence highlights:

• Research shows taurine helps regulate intracellular calcium levels, protecting neurons from excitotoxicity (over-firing), which is implicated in anxiety, neurodegeneration, and stress-related nervous system dysfunction.
• Human and animal studies suggest taurine may support stress resilience, mood balance, and central nervous system stability.
• Taurine has demonstrated neuroprotective effects in models of oxidative stress, inflammation, and mitochondrial dysfunction — all contributors to nervous system imbalance.

Benefits:

• Supports calming neurotransmission (GABAergic activity)
• Helps stabilize overactive nerves
• Supports stress adaptation and emotional regulation
• Protects neurons from oxidative and excitatory damage

Creatine: Best known for muscle energy, but it is also essential for brain energy metabolism. The brain uses large amounts of ATP (cellular energy), and creatine helps maintain energy availability in neurons, particularly during stress, cognitive demand, or sleep deprivation. Creatine is actively transported into the brain and stored as phosphocreatine, serving as a rapid energy buffer for nerve cells.

Evidence highlights:

• Human studies indicate creatine supplementation may improve cognitive performance, working memory, and mental fatigue, particularly under conditions of sleep deprivation or high stress.
• Clinical research suggests potential benefits for mood disorders, with studies showing improved depressive symptoms when creatine is used as an adjunct to conventional therapy.
• Neuroimaging studies demonstrate that creatine supports brain bioenergetics, which is critical for neurotransmitter synthesis and nerve signal transmission.

Benefits:

• Enhances neuronal energy production
• Supports mental clarity and cognitive resilience
• May improve stress tolerance and mood regulation
• Protects neurons during metabolic or oxidative stress

Resveratrol : A naturally occurring polyphenol found in grapes, berries, peanuts, and Japanese knotweed. It is widely studied for its antioxidant, anti-inflammatory, and neuroprotective properties, making it a valuable compound for supporting nervous system health. Resveratrol influences key cellular pathways involved in neuronal survival, mitochondrial function, and stress resistance, including activation of SIRT1, a longevity-associated enzyme linked to brain health.

Evidence higlights:

• Research demonstrates that resveratrol can cross the blood–brain barrier, allowing it to directly support brain and nervous system tissue.
• Human and animal studies show resveratrol helps reduce neuroinflammation and oxidative stress, both of which contribute to nervous system imbalance, cognitive decline, and mood dysregulation.
• Clinical trials in adults suggest resveratrol supplementation may improve cerebral blood flow, cognitive performance, and memory, particularly in aging populations.
• Preclinical and clinical research also indicates resveratrol may help protect neurons from excitotoxicity and mitochondrial dysfunction, key drivers of neurological stress.

Benefits:

• Supports antioxidant defense within brain and nerve tissue
• Helps regulate neuroinflammation
• Supports cognitive function and mental clarity
• Promotes neuronal resilience and healthy aging of the nervous system

Together these nutrients like magnesium threonate, glycine, omega-3s, taurine, creatine and calming botanicals, help create a comprehensive nervous system support strategy — addressing both signal regulation and cellular energy demands. Your nervous system isn’t just about feelings of calm — it’s about optimizing communication between your brain and body, managing stress responses, and maintaining cognitive health. It also has a dramatic impact on your sleep - and your nervous system repairs while sleeping.  This product combination creates a multi-layered approach to nervous system health with these essential components:

• Signal regulation (GABA, serotonin, glutamate balance)
• Energy production (ATP and mitochondrial support)
• Inflammation control (polyphenols and omega-3s)
• Neuroprotection and regeneration (antioxidants and neurotrophic factors)

Talk with your healthcare provider before introducing new supplements — especially if you’re taking medications (like SSRI’s), are pregnant/breastfeeding, or have underlying health conditions.